\u201e\u10d3\u10d8\u10e3\u10e8\u10d4\u10dc\u10d8\u10e1 \u10d9\u10e3\u10dc\u10d7\u10dd\u10d5\u10d0\u10dc\u10d8 \u10d3\u10d8\u10e1\u10e2\u10e0\u10dd\u10e4\u10d8\u10d0 \u2014 \u10e1\u10e0\u10e3\u10da\u10d8 \u10e1\u10d8\u10db\u10d0\u10e0\u10d7\u10da\u10d4: \u10db\u10d9\u10e3\u10e0\u10dc\u10d0\u10da\u10dd\u10d1\u10d8\u10e1 \u10d4\u10e4\u10d4\u10e5\u10e2\u10d8\u10d0\u10dc\u10dd\u10d1\u10d0, \u10e0\u10d8\u10e1\u10d9\u10d4\u10d1\u10d8 \u10d3\u10d0 \u10e0\u10d4\u10d2\u10e3\u10da\u10d0\u10ea\u10d8\u10d0.<\/p>\n
\u10e7\u10d5\u10d4\u10da\u10d0\u10d6\u10d4 \u10d3\u10d8\u10d3\u10d8 \u10e8\u10d4\u10ea\u10d3\u10dd\u10db\u10d0 \u10d3\u10e6\u10d4\u10e1 \u10d0\u10e0\u10d8\u10e1 \u10d8\u10e1, \u10e0\u10dd\u10db \u10e1\u10d0\u10d6\u10dd\u10d2\u10d0\u10d3\u10dd\u10d4\u10d1\u10d0\u10e1 \u10d4\u10e3\u10d1\u10dc\u10d4\u10d1\u10d8\u10d0\u10dc \u10db\u10ee\u10dd\u10da\u10dd\u10d3 \u10e4\u10d0\u10e1\u10e1 \u10d3\u10d0 \u201e\u10d8\u10db\u10d4\u10d3\u10e1\u201c, \u10db\u10d0\u10d2\u10e0\u10d0\u10db \u10d0\u10e0 \u10d4\u10e3\u10d1\u10dc\u10d4\u10d1\u10d8\u10d0\u10dc \u10e0\u10d8\u10e1\u10d9\u10d4\u10d1\u10e1. \u10db\u10d4\u10d3\u10d8\u10ea\u10d8\u10dc\u10d0\u10e8\u10d8 \u10e0\u10d8\u10e1\u10d9\u10d8\u10e1 \u10d3\u10d0\u10db\u10d0\u10da\u10d5\u10d0 \u10d0\u10e0\u10d8\u10e1 \u10e7\u10d5\u10d4\u10da\u10d0\u10d6\u10d4 \u10d3\u10d8\u10d3\u10d8 \u10e1\u10d0\u10e4\u10e0\u10d7\u10ee\u10d4\u201c, – \u10ec\u10d4\u10e0\u10e1 \u10ef\u10d0\u10dc\u10d3\u10d0\u10ea\u10d5\u10d8\u10e1 \u10d4\u10e5\u10e1\u10de\u10d4\u10e0\u10e2\u10d8 \u10d2\u10d8\u10dd\u10e0\u10d2\u10d8 \u10e4\u10ee\u10d0\u10d9\u10d0\u10eb\u10d4 7 \u10d0\u10de\u10e0\u10d8\u10da\u10e1 \u10e1\u10dd\u10ea\u10d8\u10d0\u10da\u10e3\u10e0 \u10e5\u10e1\u10d4\u10da\u10e8\u10d8 \u10d2\u10d0\u10db\u10dd\u10e5\u10d5\u10d4\u10e7\u10dc\u10d4\u10d1\u10e3\u10da \u10de\u10dd\u10e1\u10e2\u10e8\u10d8.<\/p>\n
\u201e\u10db\u10d7\u10d0\u10d5\u10d0\u10e0\u10d8 \u10e4\u10d0\u10e5\u10e2\u10d8 (\u10e0\u10d0\u10ea \u10d0\u10e3\u10ea\u10d8\u10da\u10d4\u10d1\u10da\u10d0\u10d3 \u10e3\u10dc\u10d3\u10d0 \u10d8\u10ea\u10dd\u10d3\u10d4\u10e1 \u10e1\u10d0\u10d6\u10dd\u10d2\u10d0\u10d3\u10dd\u10d4\u10d1\u10d0\u10db):<\/p>\n
\u10d3\u10d8\u10e3\u10e8\u10d4\u10dc\u10d8\u10e1 \u10db\u10d9\u10e3\u10e0\u10dc\u10d0\u10da\u10dd\u10d1\u10d0 \u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u10e3\u10e1\u10d0\u10e4\u10e0\u10d7\u10ee\u10dd, \u10db\u10d0\u10e0\u10e2\u10d8\u10d5\u10d8 \u10d0\u10dc \u10d4\u10e0\u10d7\u10ef\u10d4\u10e0\u10d0\u10d3\u10d8 \u10d2\u10d0\u10d3\u10d0\u10ec\u10e7\u10d5\u10d4\u10e2\u10d8\u10da\u10d4\u10d1\u10d0.<\/p>\n
\u10e7\u10d5\u10d4\u10da\u10d0 \u10ec\u10d0\u10db\u10d0\u10da\u10e1 \u10d0\u10e5\u10d5\u10e1: \u10e8\u10d4\u10d6\u10e6\u10e3\u10d3\u10e3\u10da\u10d8 \u10d4\u10e4\u10d4\u10e5\u10e2\u10d8, \u10e1\u10d4\u10e0\u10d8\u10dd\u10d6\u10e3\u10da\u10d8 \u10d2\u10d5\u10d4\u10e0\u10d3\u10d8\u10d7\u10d8 \u10d4\u10e4\u10d4\u10e5\u10e2\u10d4\u10d1\u10d8, \u10d2\u10d0\u10dc\u10e1\u10ee\u10d5\u10d0\u10d5\u10d4\u10d1\u10e3\u10da\u10d8 \u10e0\u10d4\u10d2\u10e3\u10da\u10d0\u10ea\u10d8\u10e3\u10e0\u10d8 \u10e1\u10e2\u10d0\u10e2\u10e3\u10e1\u10d8 (FDA vs EU).<\/p>\n
1. Elevidys (\u10d2\u10d4\u10dc\u10dd\u10d7\u10d4\u10e0\u10d0\u10de\u10d8\u10d0)<\/p>\n
FDA: \u10d3\u10d0\u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10da\u10d8\u10d0 (\u10e8\u10d4\u10d6\u10e6\u10e3\u10d3\u10e3\u10da\u10d0\u10d3).<\/p>\n
EU (EMA): \u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u10d3\u10d0\u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d8<\/p>\n
\u10e4\u10d0\u10e1\u10d8: ~3.2 \u10db\u10d8\u10da\u10d8\u10dd\u10dc\u10d8 \u10d3\u10dd\u10da\u10d0\u10e0\u10d8 (\u10d4\u10e0\u10d7\u10ef\u10d4\u10e0\u10d0\u10d3\u10d8)<\/p>\n
\u10d2\u10d5\u10d4\u10e0\u10d3\u10d8\u10d7\u10d8 \u10d4\u10e4\u10d4\u10e5\u10e2\u10d4\u10d1\u10d8 (\u10eb\u10d0\u10da\u10d8\u10d0\u10dc \u10db\u10dc\u10d8\u10e8\u10d5\u10dc\u10d4\u10da\u10dd\u10d5\u10d0\u10dc\u10d8): \u10e6\u10d5\u10d8\u10eb\u10da\u10d8\u10e1 \u10db\u10ec\u10d5\u10d0\u10d5\u10d4 \u10d3\u10d0\u10d6\u10d8\u10d0\u10dc\u10d4\u10d1\u10d0, \u10f0\u10dd\u10e1\u10de\u10d8\u10e2\u10d0\u10da\u10d8\u10d6\u10d0\u10ea\u10d8\u10d0, \u10d3\u10d0\u10e4\u10d8\u10e5\u10e1\u10d8\u10e0\u10d4\u10d1\u10e3\u10da\u10d8\u10d0 \u10e1\u10d8\u10d9\u10d5\u10d3\u10d8\u10da\u10d8\u10e1 \u10e8\u10d4\u10db\u10d7\u10ee\u10d5\u10d4\u10d5\u10d4\u10d1\u10d8, \u10db\u10d8\u10dd\u10d9\u10d0\u10e0\u10d3\u10d8\u10e2\u10d8 (\u10d2\u10e3\u10da\u10d8\u10e1 \u10d0\u10dc\u10d7\u10d4\u10d1\u10d0), \u10db\u10d8\u10dd\u10d6\u10d8\u10e2\u10d8 (\u10d9\u10e3\u10dc\u10d7\u10d8\u10e1 \u10d0\u10dc\u10d7\u10d4\u10d1\u10d0), \u10d8\u10db\u10e3\u10dc\u10e3\u10e0\u10d8 \u10e0\u10d4\u10d0\u10e5\u10ea\u10d8\u10d4\u10d1\u10d8.<\/p>\n
FDA \u10e3\u10d9\u10d5\u10d4 \u10d8\u10eb\u10d8\u10d4\u10d1\u10e1 \u10d0\u10db \u10e8\u10d4\u10db\u10d7\u10ee\u10d5\u10d4\u10d5\u10d4\u10d1\u10e1 \u10d3\u10d0 \u10d3\u10d0\u10d0\u10db\u10d0\u10e2\u10d0 \u10db\u10d9\u10d0\u10ea\u10e0\u10d8 \u10d2\u10d0\u10e4\u10e0\u10d7\u10ee\u10d8\u10da\u10d4\u10d1\u10d4\u10d1\u10d8.<\/p>\n
\u10eb\u10d0\u10da\u10d8\u10d0\u10dc \u10db\u10dc\u10d8\u10e8\u10d5\u10dc\u10d4\u10da\u10dd\u10d5\u10d0\u10dc\u10d8: \u10d4\u10e1 \u10d7\u10d4\u10e0\u10d0\u10de\u10d8\u10d0 \u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u10e7\u10d5\u10d4\u10da\u10d0 \u10de\u10d0\u10ea\u10d8\u10d4\u10dc\u10e2\u10d8\u10e1\u10d7\u10d5\u10d8\u10e1, \u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u10e1\u10e0\u10e3\u10da\u10d0\u10d3 \u10e3\u10e1\u10d0\u10e4\u10e0\u10d7\u10ee\u10dd, \u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u201e\u10e1\u10d0\u10e1\u10ec\u10d0\u10e3\u10da\u10d8 \u10d2\u10d0\u10db\u10dd\u10e1\u10d0\u10d5\u10d0\u10da\u10d8\u201c.<\/p>\n
2. Duvyzat (givinostat)<\/p>\n
FDA: \u10d3\u10d0\u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d8\u10d0 (2024)<\/p>\n
EU: \u10d3\u10d0\u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d8\u10d0<\/p>\n
\u10e4\u10d0\u10e1\u10d8: ~700,000$\/\u10ec\u10d4\u10da\u10d8\u10ec\u10d0\u10d3\u10e8\u10d8<\/p>\n
\u10d2\u10d5\u10d4\u10e0\u10d3\u10d8\u10d7\u10d8 \u10d4\u10e4\u10d4\u10e5\u10e2\u10d4\u10d1\u10d8: \u10d3\u10d8\u10d0\u10e0\u10d4\u10d0, \u10d2\u10e3\u10da\u10d8\u10e1\u10e0\u10d4\u10d5\u10d0 \/ \u10e6\u10d4\u10d1\u10d8\u10dc\u10d4\u10d1\u10d0, \u10d7\u10e0\u10dd\u10db\u10d1\u10dd\u10ea\u10d8\u10e2\u10d4\u10d1\u10d8\u10e1 \u10e8\u10d4\u10db\u10ea\u10d8\u10e0\u10d4\u10d1\u10d0 (\u10e1\u10d8\u10e1\u10ee\u10da\u10d3\u10d4\u10dc\u10d8\u10e1 \u10e0\u10d8\u10e1\u10d9\u10d8), \u10ea\u10ee\u10d8\u10db\u10d4\u10d1\u10d8\u10e1 \u10db\u10d0\u10e2\u10d4\u10d1\u10d0 \u10e1\u10d8\u10e1\u10ee\u10da\u10e8\u10d8, \u10e1\u10d8\u10ea\u10ee\u10d4.<\/p>\n
3. Agamree (vamorolone)<\/p>\n
FDA: \u10d3\u10d0\u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d8\u10d0 (2023)<\/p>\n
EU: \u10d3\u10d0\u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d8\u10d0<\/p>\n
\u10e4\u10d0\u10e1\u10d8: ~50,000\u2013100,000$\/\u10ec\u10d4\u10da\u10d8\u10ec\u10d0\u10d3\u10e8\u10d8<\/p>\n
\u10d2\u10d5\u10d4\u10e0\u10d3\u10d8\u10d7\u10d8 \u10d4\u10e4\u10d4\u10e5\u10e2\u10d4\u10d1\u10d8: \u10f0\u10dd\u10e0\u10db\u10dd\u10dc\u10d0\u10da\u10e3\u10e0\u10d8 \u10d3\u10d0\u10e0\u10e6\u10d5\u10d4\u10d5\u10d4\u10d1\u10d8 (Cushing-like), \u10ec\u10dd\u10dc\u10d8\u10e1 \u10db\u10d0\u10e2\u10d4\u10d1\u10d0, \u10e4\u10e1\u10d8\u10e5\u10d8\u10d9\u10e3\u10e0\u10d8 \u10ea\u10d5\u10da\u10d8\u10da\u10d4\u10d1\u10d4\u10d1\u10d8 (\u10d0\u10d2\u10e0\u10d4\u10e1\u10d8\u10d0, \u10e8\u10e4\u10dd\u10d7\u10d5\u10d0), \u10d8\u10db\u10e3\u10dc\u10d8\u10e2\u10d4\u10e2\u10d8\u10e1 \u10d3\u10d0\u10e5\u10d5\u10d4\u10d8\u10d7\u10d4\u10d1\u10d0, \u10d8\u10dc\u10e4\u10d4\u10e5\u10ea\u10d8\u10d4\u10d1\u10d8\u10e1 \u10e0\u10d8\u10e1\u10d9\u10d8, \u10d0\u10d3\u10e0\u10d4\u10dc\u10d0\u10da\u10e3\u10e0\u10d8 \u10e3\u10d9\u10db\u10d0\u10e0\u10d8\u10e1\u10dd\u10d1\u10d0.<\/p>\n
4. Exon-skipping \u10de\u10e0\u10d4\u10de\u10d0\u10e0\u10d0\u10e2\u10d4\u10d1\u10d8 (Exondys, Vyondys \u10d3\u10d0 \u10e1\u10ee\u10d5.)<\/p>\n
FDA: \u10d3\u10d0\u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d8\u10d0 (Accelerated approval)<\/p>\n
EU: \u10eb\u10d8\u10e0\u10d8\u10d7\u10d0\u10d3\u10d0\u10d3, \u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u10d3\u10d0\u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d8<\/p>\n
\u10e4\u10d0\u10e1\u10d8: ~300,000 \u2013 1,000,000+$\/\u10ec\u10d4\u10da\u10d8\u10ec\u10d0\u10d3\u10e8\u10d8<\/p>\n
\u10d2\u10d5\u10d4\u10e0\u10d3\u10d8\u10d7\u10d8 \u10d4\u10e4\u10d4\u10e5\u10e2\u10d4\u10d1\u10d8: \u10d8\u10dc\u10e4\u10d4\u10e5\u10ea\u10d8\u10d4\u10d1\u10d8, \u10ee\u10d5\u10d4\u10da\u10d0, \u10e1\u10d8\u10ea\u10ee\u10d4, \u10d7\u10d8\u10e0\u10d9\u10db\u10da\u10d8\u10e1 \u10d2\u10d0\u10e0\u10d7\u10e3\u10da\u10d4\u10d1\u10d4\u10d1\u10d8, \u10d8\u10dc\u10d4\u10e5\u10ea\u10d8\u10d8\u10e1 \u10d0\u10d3\u10d2\u10d8\u10da\u10d6\u10d4 \u10e0\u10d4\u10d0\u10e5\u10ea\u10d8\u10d4\u10d1\u10d8, \u10e6\u10d4\u10d1\u10d8\u10dc\u10d4\u10d1\u10d0, \u10d2\u10d0\u10db\u10dd\u10dc\u10d0\u10e7\u10d0\u10e0\u10d8, \u10e1\u10d0\u10ee\u10e1\u10e0\u10d4\u10d1\u10d8\u10e1 \u10e2\u10d9\u10d8\u10d5\u10d8\u10da\u10d8.<\/p>\n
\u10eb\u10d0\u10da\u10d8\u10d0\u10dc \u10db\u10dc\u10d8\u10e8\u10d5\u10dc\u10d4\u10da\u10dd\u10d5\u10d0\u10dc\u10d8: \u10db\u10e3\u10e8\u10d0\u10dd\u10d1\u10e1 \u10db\u10ee\u10dd\u10da\u10dd\u10d3 5-15% \u10de\u10d0\u10ea\u10d8\u10d4\u10dc\u10e2\u10d6\u10d4 (\u10d2\u10d4\u10dc\u10d4\u10e2\u10d8\u10d9\u10d8\u10e1 \u10db\u10d8\u10ee\u10d4\u10d3\u10d5\u10d8\u10d7)<\/p>\n
5. \u10e1\u10e2\u10d0\u10dc\u10d3\u10d0\u10e0\u10e2\u10e3\u10da\u10d8 \u10d7\u10d4\u10e0\u10d0\u10de\u10d8\u10d0 (Deflazacort)<\/p>\n
FDA: \u10d3\u10d0\u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d8\u10d0<\/p>\n
EU: \u10d3\u10d0\u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d8\u10d0<\/p>\n
\u10e4\u10d0\u10e1\u10d8: ~35,000\u201360,000$\/\u10ec\u10d4\u10da\u10d8\u10ec\u10d0\u10d3\u10e8\u10d8<\/p>\n
\u10d2\u10d5\u10d4\u10e0\u10d3\u10d8\u10d7\u10d8 \u10d4\u10e4\u10d4\u10e5\u10e2\u10d4\u10d1\u10d8: \u10d6\u10e0\u10d3\u10d8\u10e1 \u10e8\u10d4\u10e4\u10d4\u10e0\u10ee\u10d4\u10d1\u10d0, \u10dd\u10e1\u10e2\u10d4\u10dd\u10de\u10dd\u10e0\u10dd\u10d6\u10d8, \u10d3\u10d8\u10d0\u10d1\u10d4\u10e2\u10d8\u10e1 \u10e0\u10d8\u10e1\u10d9\u10d8, \u10ec\u10dd\u10dc\u10d8\u10e1 \u10db\u10d0\u10e2\u10d4\u10d1\u10d0, \u10d8\u10dc\u10e4\u10d4\u10e5\u10ea\u10d8\u10d4\u10d1\u10d8<\/p>\n
\u10db\u10dd\u10db\u10d0\u10d5\u10d0\u10da\u10d8 \u10d7\u10d4\u10e0\u10d0\u10de\u10d8\u10d4\u10d1\u10d8 (\u10ef\u10d4\u10e0 \u10d9\u10d5\u10da\u10d4\u10d5\u10d8\u10e1 \u10d4\u10e2\u10d0\u10de\u10d6\u10d4\u10d0)<\/p>\n
CRISPR \u10d2\u10d4\u10dc\u10e3\u10e0\u10d8 \u10e0\u10d4\u10d3\u10d0\u10e5\u10e2\u10d8\u10e0\u10d4\u10d1\u10d0<\/p>\n
\u10d0\u10ee\u10d0\u10da\u10d8 \u10d2\u10d4\u10dc\u10dd\u10d7\u10d4\u10e0\u10d0\u10de\u10d8\u10d4\u10d1\u10d8 (\u10e3\u10e4\u10e0\u10dd \u10e3\u10e1\u10d0\u10e4\u10e0\u10d7\u10ee\u10dd \u10d5\u10d0\u10e0\u10d8\u10d0\u10dc\u10e2\u10d4\u10d1\u10d8)<\/p>\n
\u10d9\u10dd\u10db\u10d1\u10d8\u10dc\u10d8\u10e0\u10d4\u10d1\u10e3\u10da\u10d8 \u10db\u10d9\u10e3\u10e0\u10dc\u10d0\u10da\u10dd\u10d1\u10d0<\/p>\n
\u10db\u10d0\u10d2\u10e0\u10d0\u10db: \u10ef\u10d4\u10e0 \u10d0\u10e0\u10ea\u10d4\u10e0\u10d7\u10d8 \u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u10e1\u10e0\u10e3\u10da\u10d0\u10d3 \u10d3\u10d0\u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d8.<\/p>\n
\u10e7\u10d5\u10d4\u10da\u10d0\u10d6\u10d4 \u10db\u10dc\u10d8\u10e8\u10d5\u10dc\u10d4\u10da\u10dd\u10d5\u10d0\u10dc\u10d8 \u10d3\u10d0\u10e1\u10d9\u10d5\u10dc\u10d0:<\/p>\n
\u10d3\u10e6\u10d4\u10e1 \u10d0\u10e0\u10ea\u10d4\u10e0\u10d7\u10d8 \u10d7\u10d4\u10e0\u10d0\u10de\u10d8\u10d0<\/p>\n
\u274c\u10d0\u10e0 \u10d9\u10e3\u10e0\u10dc\u10d0\u10d5\u10e1 \u10d3\u10d0\u10d0\u10d5\u10d0\u10d3\u10d4\u10d1\u10d0\u10e1<\/p>\n
\u274c\u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u10e1\u10e0\u10e3\u10da\u10d0\u10d3 \u10e3\u10e1\u10d0\u10e4\u10e0\u10d7\u10ee\u10dd<\/p>\n
\u274c\u10d0\u10e0 \u10d0\u10e0\u10d8\u10e1 \u10e3\u10dc\u10d8\u10d5\u10d4\u10e0\u10e1\u10d0\u10da\u10e3\u10e0\u10d8<\/p>\n
\u10e0\u10d4\u10d0\u10da\u10e3\u10e0\u10d8 \u10d0\u10e0\u10e9\u10d4\u10d5\u10d0\u10dc\u10d8 \u10e5\u10d5\u10d4\u10e7\u10dc\u10d8\u10e1\u10d7\u10d5\u10d8\u10e1 –<\/p>\n
100 \u10de\u10d0\u10ea\u10d8\u10d4\u10dc\u10e2\u10d8 =<\/p>\n
\u10d2\u10d4\u10dc\u10dd\u10d7\u10d4\u10e0\u10d0\u10de\u10d8\u10d0 \u2192 ~300 \u10db\u10d8\u10da\u10d8\u10dd\u10dc\u10d8 $<\/p>\n
\u10d7\u10d0\u10dc\u10d0\u10db\u10d4\u10d3\u10e0\u10dd\u10d5\u10d4 \u10ec\u10d0\u10db\u10da\u10d4\u10d1\u10d8 \u2192 5\u201370 \u10db\u10d8\u10da\u10d8\u10dd\u10dc\u10d8 $\/\u10ec\u10d4\u10da\u10d8\u10ec\u10d0\u10d3\u10e8\u10d8<\/p>\n
\u10eb\u10d0\u10da\u10d8\u10d0\u10dc \u10db\u10d9\u10d0\u10e4\u10d8\u10dd \u10d3\u10d0\u10e1\u10d9\u10d5\u10dc\u10d0 – \u10db\u10e8\u10dd\u10d1\u10da\u10d4\u10d1\u10d8\u10e1 \u10db\u10dd\u10d7\u10ee\u10dd\u10d5\u10dc\u10d0 \u10d0\u10e0\u10d8\u10e1 \u10e1\u10d0\u10db\u10d0\u10e0\u10d7\u10da\u10d8\u10d0\u10dc\u10d8. \u10db\u10d0\u10d2\u10e0\u10d0\u10db:<\/p>\n
\u10e1\u10e0\u10e3\u10da\u10d8 \u10e1\u10d8\u10db\u10d0\u10e0\u10d7\u10da\u10d8\u10e1 \u10d2\u10d0\u10e0\u10d4\u10e8\u10d4, \u10d4\u10e1 \u10ee\u10d3\u10d4\u10d1\u10d0 \u10db\u10d0\u10dc\u10d8\u10de\u10e3\u10da\u10d0\u10ea\u10d8\u10d0.<\/p>\n
\u10db\u10d4\u10d3\u10d8\u10ea\u10d8\u10dc\u10d0 – \u10d4\u10e1 \u10d0\u10e0\u10d8\u10e1: \u10d4\u10e4\u10d4\u10e5\u10e2\u10d8\u10d0\u10dc\u10dd\u10d1\u10d0, \u10e3\u10e1\u10d0\u10e4\u10e0\u10d7\u10ee\u10dd\u10d4\u10d1\u10d0, \u10db\u10e2\u10d9\u10d8\u10ea\u10d4\u10d1\u10e3\u10da\u10d4\u10d1\u10d0 \u10d3\u10d0 \u10d0\u10e0\u10d0 \u10d4\u10db\u10dd\u10ea\u10d8\u10d0, \u10de\u10dd\u10da\u10d8\u10e2\u10d8\u10d9\u10d0, \u10dc\u10d0\u10ee\u10d4\u10d5\u10d0\u10e0\u10d8 \u10e1\u10d8\u10db\u10d0\u10e0\u10d7\u10da\u10d4”, – \u10ec\u10d4\u10e0\u10e1 \u10d2\u10d8\u10dd\u10e0\u10d2\u10d8 \u10e4\u10ee\u10d0\u10d9\u10d0\u10eb\u10d4.<\/p>\n","protected":false},"excerpt":{"rendered":"
\u201e\u10d3\u10d8\u10e3\u10e8\u10d4\u10dc\u10d8\u10e1 \u10d9\u10e3\u10dc\u10d7\u10dd\u10d5\u10d0\u10dc\u10d8 \u10d3\u10d8\u10e1\u10e2\u10e0\u10dd\u10e4\u10d8\u10d0 \u2014 \u10e1\u10e0\u10e3\u10da\u10d8 \u10e1\u10d8\u10db\u10d0\u10e0\u10d7\u10da\u10d4: \u10db\u10d9\u10e3\u10e0\u10dc\u10d0\u10da\u10dd\u10d1\u10d8\u10e1 \u10d4\u10e4\u10d4\u10e5\u10e2\u10d8\u10d0\u10dc\u10dd\u10d1\u10d0, \u10e0\u10d8\u10e1\u10d9\u10d4\u10d1\u10d8 \u10d3\u10d0 \u10e0\u10d4\u10d2\u10e3\u10da\u10d0\u10ea\u10d8\u10d0. \u10e7\u10d5\u10d4\u10da\u10d0\u10d6\u10d4 \u10d3\u10d8\u10d3\u10d8 \u10e8\u10d4\u10ea\u10d3\u10dd\u10db\u10d0 \u10d3\u10e6\u10d4\u10e1 \u10d0\u10e0\u10d8\u10e1 \u10d8\u10e1, \u10e0\u10dd\u10db \u10e1\u10d0\u10d6\u10dd\u10d2\u10d0\u10d3\u10dd\u10d4\u10d1\u10d0\u10e1 \u10d4\u10e3\u10d1\u10dc\u10d4\u10d1\u10d8\u10d0\u10dc \u10db\u10ee\u10dd\u10da\u10dd\u10d3 \u10e4\u10d0\u10e1\u10e1 \u10d3\u10d0 \u201e\u10d8\u10db\u10d4\u10d3\u10e1\u201c, \u10db\u10d0\u10d2\u10e0\u10d0\u10db \u10d0\u10e0 \u10d4\u10e3\u10d1\u10dc\u10d4\u10d1\u10d8\u10d0\u10dc \u10e0\u10d8\u10e1\u10d9\u10d4\u10d1\u10e1. \u10db\u10d4\u10d3\u10d8\u10ea\u10d8\u10dc\u10d0\u10e8\u10d8 \u10e0\u10d8\u10e1\u10d9\u10d8\u10e1 \u10d3\u10d0\u10db\u10d0\u10da\u10d5\u10d0 \u10d0\u10e0\u10d8\u10e1 \u10e7\u10d5\u10d4\u10da\u10d0\u10d6\u10d4 \u10d3\u10d8\u10d3\u10d8 \u10e1\u10d0\u10e4\u10e0\u10d7\u10ee\u10d4\u201c, – \u10ec\u10d4\u10e0\u10e1 \u10ef\u10d0\u10dc\u10d3\u10d0\u10ea\u10d5\u10d8\u10e1 \u10d4\u10e5\u10e1\u10de\u10d4\u10e0\u10e2\u10d8 \u10d2\u10d8\u10dd\u10e0\u10d2\u10d8 \u10e4\u10ee\u10d0\u10d9\u10d0\u10eb\u10d4 7 \u10d0\u10de\u10e0\u10d8\u10da\u10e1 \u10e1\u10dd\u10ea\u10d8\u10d0\u10da\u10e3\u10e0 \u10e5\u10e1\u10d4\u10da\u10e8\u10d8 \u10d2\u10d0\u10db\u10dd\u10e5\u10d5\u10d4\u10e7\u10dc\u10d4\u10d1\u10e3\u10da \u10de\u10dd\u10e1\u10e2\u10e8\u10d8. \u201e\u10db\u10d7\u10d0\u10d5\u10d0\u10e0\u10d8 \u10e4\u10d0\u10e5\u10e2\u10d8 (\u10e0\u10d0\u10ea \u10d0\u10e3\u10ea\u10d8\u10da\u10d4\u10d1\u10da\u10d0\u10d3 \u10e3\u10dc\u10d3\u10d0 \u10d8\u10ea\u10dd\u10d3\u10d4\u10e1 \u10e1\u10d0\u10d6\u10dd\u10d2\u10d0\u10d3\u10dd\u10d4\u10d1\u10d0\u10db): \u10d3\u10d8\u10e3\u10e8\u10d4\u10dc\u10d8\u10e1 […]<\/p>\n","protected":false},"author":2,"featured_media":8064,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[18,62],"tags":[],"class_list":{"0":"post-8063","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-axali-ambebi","8":"category-sazogadoeba"},"acf":[],"_links":{"self":[{"href":"https:\/\/postvmedia.ge\/index.php?rest_route=\/wp\/v2\/posts\/8063","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/postvmedia.ge\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/postvmedia.ge\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/postvmedia.ge\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/postvmedia.ge\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=8063"}],"version-history":[{"count":1,"href":"https:\/\/postvmedia.ge\/index.php?rest_route=\/wp\/v2\/posts\/8063\/revisions"}],"predecessor-version":[{"id":8065,"href":"https:\/\/postvmedia.ge\/index.php?rest_route=\/wp\/v2\/posts\/8063\/revisions\/8065"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/postvmedia.ge\/index.php?rest_route=\/wp\/v2\/media\/8064"}],"wp:attachment":[{"href":"https:\/\/postvmedia.ge\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=8063"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/postvmedia.ge\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=8063"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/postvmedia.ge\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=8063"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}